Chemokine CCL25 Induces Migration and Extracellular Matrix Production of Anulus Fibrosus-Derived Cells
نویسندگان
چکیده
منابع مشابه
Investigation of anulus fibrosus morphology
main reasons for workforce losses. Disc herniation is important as it both causes symptoms and requires prolonged treatment. Intervertebral discs are 23 formations existing between adjacent surfaces of the vertebral bodies from the axis to the sacrum.1 The area surrounding the nucleus pulposus consists of fibers, which include a number of chondrocytes. Therefore, the tissue is known as "fibroca...
متن کاملQuantification of Extracellular Matrix Proteins in the Nucleus Pulposus and Anulus Fibrosus of the Human Intervertebral Disc: Variation with Aging
*Singh, K; *Masuda, K; *Thonar, E.; *An, H; +*Cs-Szabo, G +* Rush University Medical Center, Chicago, IL [email protected] INTRODUCTION: The functions of the intervertebral disc (IVD) as a unit, and of the annulus fibrosus (AF) and nucleus pulposus (NP) individually, are determined by the molecular composition of their extracellular matrices (ECM). The outerand inner-AF consists of large collag...
متن کاملEffect of extracellular matrix on testosterone production during in vitro culture of bovine testicular cells
Testosterone is believed to play a significant role in spermatogenesis, but its contribution to the process of spermatogenesis is not completely understood. Given that extracellular matrix (ECM) facilitates differentiation of spermatogonial stem cells (SSCs) during culture, the present study was conducted to elucidate whether testosterone contribute to the permissive effect of ECM on SSCs diffe...
متن کاملPlatelet-rich plasma (PRP) stimulates the extracellular matrix metabolism of porcine nucleus pulposus and anulus fibrosus cells cultured in alginate beads.
STUDY DESIGN In vitro assessment of the effects of platelet-rich plasma on the extracellular matrix metabolism of porcine intervertebral disc cells. OBJECTIVES To determine whether platelet-rich plasma is effective in stimulating cell proliferation and extracellular matrix metabolism by porcine disc cells cultured in alginate beads. SUMMARY OF BACKGROUND DATA Platelet-rich plasma is used to...
متن کاملChemically primed bone-marrow derived mesenchymal stem cells show enhanced expression of chemokine receptors contributed to their migration capability
Objective(s):The limited homing potential of bone-marrow-derived mesenchymal stem cells (BM-MSC) is the key obstacle in MSC-based therapy. It is believed that chemokines and chemokine receptor interactions play key roles in cellular processes associated with migration. Meanwhile, MSCs express a low level of distinct chemokine receptors and they even lose these receptors on their surface after a...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2018
ISSN: 1422-0067
DOI: 10.3390/ijms19082207